Normalized Counts

Download M1_v_NTC.csv

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Download M4_v_NTC.csv

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M1 (n=3) and M4 (n=3) were pooled together and compared against NTC (n=3)

Download KD_v_NTC.csv

PCA

Hierarchical clustering

Correlation Heatmap

Volcano

M1 vs NTC

M4 vs NTC

KD vs NTC

M1 and M4 were pooled together and compared against NTC. *Note the unbalanced comparison: n=6 for MED4KD (3 reps for M1 and 3 reps for M4) vs. n=3 for NTC

Pathway Analysis

Using criteria of log2FC > 2 and FDR < 0.05

M1 v NTC

Upregulated

Downregulated

M4 v NTC

Upregulated

Downregulated

KD v NTC

Upregulated

Downregulated

GSEA

M1 v NTC

M4 v NTC

KD v NTC